Win 55212-2

• 产品号: W498850
• CAS号: 131543-22-1
• 分子式: C29H30N2O3
• 分子量: 454.5601

产品别名

• 标题: Win 55212-2
• IUPAC标准名: 2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^4,^1^2]dodeca-2,4,6,8(12)-tetraene; ethene
• IUPAC传统名: 2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.0^4,^1^2]dodeca-2,4,6,8(12)-tetraene; ethylene
• 别名: Win 2; (R)-(+)-Win 55212-2; (R)-[2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone; (R)-Win 55212; [(3R)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone

产品登记号

• CAS号: 131543-22-1

产品详细信息

详细说明 (English)

A synthetic CB1/CB2 cannabinoid receptor agonist. It is potent analgesic and has anti-inflammatory properties. It activates p42 and p44 MAP kinase via receptor-mediated signaling.

参考文献

• Meng, I.D. et al.: Nature, 395, 381 (1998)
• Bouaboula, M. et al. Biochem. J., 312, 637 (1998)
• Niederhoffer, N. et al.: Br. J. Pharamcol., 126, 457 (1998)
• Marchalant, Y. et al.: Neurosci., 144, 1516 (1998)