Voclosporin

• 产品号: V678500
• CAS号: 515814-01-4
• 分子式: C32H57N3O5
• 分子量: 563.81208

产品别名

• 标题: Voclosporin
• IUPAC标准名: (3E,6R,17S)-8-(dimethylamino)-6,18-dimethyl-17-[(2S)-4-methyl-2-(methylamino)pentanamido]-9,16-dioxononadeca-1,3-dien-7-yl acetate
• IUPAC传统名: (3E,6R,17S)-8-(dimethylamino)-6,18-dimethyl-17-[(2S)-4-methyl-2-(methylamino)pentanamido]-9,16-dioxononadeca-1,3-dien-7-yl acetate
• 别名: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A; trans-ISA 247; R 1524; ISATX 247

产品登记号

• CAS号: 515814-01-4

产品详细信息

详细说明 (English)

A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin

参考文献

• Aspeslet, L., et al.: Transplant Proc., 33, 1048 (2001)
• Cho, M., et al.: Arthritis Rheum., 46, 1202 (2001)
• Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2001)