Verapamil Ethyl Methanethiosulfonate, Bromide

• 产品号: V125100
• CAS号: 353270-25-4
• 分子式: C30H45BrN2O6S2
• 分子量: 673.7221
• 保 存: Amber Vial, Refrigerator, Under Inert Atmosphere

产品别名

• 标题: Verapamil Ethyl Methanethiosulfonate, Bromide
• IUPAC标准名: [4-cyano-4-(3,4-dimethoxyphenyl)-4-(propan-2-yl)butyl][2-(3,4-dimethoxyphenyl)ethyl][2-(methanesulfonylsulfanyl)ethyl](methyl)azanium bromide
• IUPAC传统名: [4-cyano-4-(3,4-dimethoxyphenyl)-4-isopropylbutyl][2-(3,4-dimethoxyphenyl)ethyl][2-(methanesulfonylsulfanyl)ethyl](methyl)azanium bromide
• 别名: δ-Cyano-N-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dimethoxy-N-methyl-δ-(1-methylethyl)-N-[2-[(methylsulfonyl)thio]ethyl]benzenebutanaminium Bromide

产品登记号

• CAS号: 353270-25-4

产品性质

• 外观: White to Off-White Solid
• 熔点: 105-110°C (foaming)
• 溶解度: Dichloromethane
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Amber Vial, Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An analog of Verapamil. P Glycoprotein drug binding domain verapamil methanethiosulfonate. Useful for mapping the pore region of L-type calcium channels and Kv1.3 potassium channels.

参考文献

• Loo, T., et al.: J. Biol. Chem., 270, 843 (1995)
• Sharom, F., et al.: J. Membr. Biol., 160, 161 (1995)
• Kim, R., et al.: J. Clin. Invest., 101, 289 (1995)
• Lee, C., et al.: Biochemistry., 37, 3594 (1995)