24-O-Triisopropylsilyl 9-Norketo FK-506

• 产品号: T795540
• 分子式: C52H89NO11Si
• 分子量: 932.34866

产品别名

• 标题: 24-O-Triisopropylsilyl 9-Norketo FK-506
• IUPAC标准名: (1R,8S,11S,12S,13S,16R,17E,20S,22S,23R,24R,26R)-1-hydroxy-11-[(1E)-1-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-22,24-dimethoxy-12,18,20,26-tetramethyl-16-(prop-2-en-1-yl)-13-{[tris(propan-2-yl)silyl]oxy}-10,27-dioxa-3-azatricyclo[21.3.1.0^3,^8]heptacos-17-ene-2,9,15-trione
• IUPAC传统名: (1R,8S,11S,12S,13S,16R,17E,20S,22S,23R,24R,26R)-1-hydroxy-11-[(1E)-1-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-22,24-dimethoxy-12,18,20,26-tetramethyl-16-(prop-2-en-1-yl)-13-[(triisopropylsilyl)oxy]-10,27-dioxa-3-azatricyclo[21.3.1.0^3,^8]heptacos-17-ene-2,9,15-trione
• 别名: [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,25aR*]]- 3,4,5,6,8,11,12,13,14,15,16,17,18,19,23,24,25,25a-Octadecahydro-5-O-Triisopropylsilyl-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclodocosine-1,7,20(22H)-trione

产品性质

• 外观: Colorless Oil
• 溶解度: Chloroform
• 溶解度: Dichloromethane

产品详细信息

详细说明 (English)

Protected FK-506 (F370000) impurity. A FK-506 derivative prepared via base-mediated FK-506 rearrangement and oxidation.

参考文献

• Askin, D., et al.: Tetrahedron Lett., 30, 671 (1989)