N-Trifluoroacetyl-8-(2-tert-butyl(dimethyl)silyl]oxy) Doxorubicin

• 产品号: T786760
• 分子式: C35H42F3NO12S
• 分子量: 757.7676896

产品别名

• 标题: N-Trifluoroacetyl-8-(2-tert-butyl(dimethyl)silyl]oxy) Doxorubicin
• IUPAC标准名: N-[(2S,3S,4S,6S)-6-{[(1S,3S)-3-{2-[(tert-butyldimethyl-λ^4-sulfanyl)oxy]acetyl}-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy}-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide
• IUPAC传统名: N-[(2S,3S,4S,6S)-6-{[(1S,3S)-3-{2-[(tert-butyldimethyl-λ^4-sulfanyl)oxy]acetyl}-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy}-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide
• 别名: (1S,3S)-2,3,6-Trideoxy-3-(2,2,2-trifluoroacetamido)-3-ert-butyl(dimethyl)silylglycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl-α-L-lyxo-hexopyranoside; N-Trifluoroacetyl-8-(2-tert-butyl(dimethyl)silyl]oxy)adriamycin

产品性质

• 外观: Dark Red Crystals
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate

产品详细信息

详细说明 (English)

Doxorubicin (D558000) metabolite. Cytotoxic interaction with DNA.

参考文献

• Potmesil, M. et al.: Eur. J. Cancer Clin. On. 19, 109 (1983)
• Bodley, A., et al.: Cancer Res. 49, 5969 (1989)