7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel-d5

• 产品号: T774147
• 分子式: C50H52Cl3NO16
• 分子量: 1029.30398

产品别名

• 标题: 7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel-d5
• IUPAC标准名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1-hydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-[(^2H₅)phenylformamido]propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1-hydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-[(^2H₅)phenylformamido]propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-9-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• 别名: 7-(2,2,2-Trichloroethyloxycarbonyl)taxol-d5; (αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic acid, , (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester-d5

产品性质

• 外观: Off-White Powder
• 溶解度: Chloroform
• 溶解度: Ethyl Acetate

产品详细信息

详细说明 (English)

Labelled 7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel is used in the semi-synthesis of Taxol (P132500) and Docetaxel (D494420).

参考文献

• Commercon, A., et al.: Tetrahedr. Lett., 33, 5185 (1992)