Topotecan-d5

• 产品号: T542503
• CAS号: 1133355-98-2
• 分子式: C23H23N3O5
• 分子量: 421.44582
• 保 存: -20°C Freezer

产品别名

• 标题: Topotecan-d5
• IUPAC标准名: (19S)-8-[(dimethylamino)methyl]-19-(^2H₅)ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
• IUPAC传统名: (19S)-8-[(dimethylamino)methyl]-19-(^2H₅)ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
• 别名: NSC-609669-d5; Hycamtin-d5; (4S)-10-[(Dimethylamino)methyl]-4-(ethyl-d5)-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; SKF-104864A-d5

产品登记号

• CAS号: 1133355-98-2

产品性质

• 外观: Yellow Solid
• 熔点: >200°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol (Sparingly)
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Labelled Topotecan (T542500). A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic.

参考文献

• Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990)
• BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1990)
• Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1990)