Topotecan-d6

• 产品号: T542502
• CAS号: 1044904-10-0
• 分子式: C23H23N3O5
• 分子量: 421.44582
• 保 存: -20°C Freezer

产品别名

• 标题: Topotecan-d6
• IUPAC标准名: (19S)-8-{[bis(^2H₃)methylamino]methyl}-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
• IUPAC传统名: (19S)-8-{[bis(^2H₃)methylamino]methyl}-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
• 别名: SKF-104864A-d6; Hycamtin-d6; NSC-609669-d6; (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

产品登记号

• CAS号: 1044904-10-0

产品性质

• 外观: Yellow Solid
• 熔点: >250°C(dec.)
• 溶解度: Acidic Water
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Labelled Topotecan (T542500). A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic.

参考文献

• Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990)
• BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1990)
• Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1990)