Tolafentrine

• 产品号: T531000
• CAS号: 139308-65-9
• 分子式: C28H31N3O4S
• 分子量: 505.62844

产品别名

• 标题: Tolafentrine
• IUPAC标准名: N-{4-[(4aS,10bR)-8,9-dimethoxy-2-methyl-1H,2H,3H,4H,4aH,10bH-benzo[c]1,6-naphthyridin-6-yl]phenyl}-4-methylbenzene-1-sulfonamide
• IUPAC传统名: N-{4-[(4aS,10bR)-8,9-dimethoxy-2-methyl-1H,3H,4H,4aH,10bH-benzo[c]1,6-naphthyridin-6-yl]phenyl}-4-methylbenzenesulfonamide
• 别名: rel-(-)-N-[4-[(4aR,10bS)-1,2,3,4,4a,10b-Hexahydro-8,9-dimethoxy-2-methylbenzo[c][1,6]naphthyridin-6-yl]phenyl]-4-methylbenzenesulfonamide

产品登记号

• CAS号: 139308-65-9

产品详细信息

详细说明 (English)

A dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.

参考文献

• Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990)
• Tanaka, K., et al.: Cancer Res., 55, 2927 (1990)
• Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1990)
• Cowan, K., et al.: Nat. Med., 6, 698 (1990)
• Shankavaram, U., et al.: J. Biol. Chem.,