Ticagrelor

• 产品号: T437700
• CAS号: 274693-27-5
• 分子式: C23H28F2N6O4S
• 分子量: 522.5680264
• 保 存: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品别名

• 标题: Ticagrelor
• IUPAC标准名: (1S,2S,3R,5S)-3-(7-{[(1R)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• IUPAC传统名: (1S,2S,3R,5S)-3-(7-{[(1R)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• 别名: AZD 6140; (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-D1,2-Cyclopentanediolifluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol; AR-C 126532XX

产品登记号

• CAS号: 274693-27-5

产品性质

• 外观: White Solid
• 熔点: 149-154°C
• 溶解度: Chloroform
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).

参考文献

• Matetzky, S., et al.: Circulation, 109, 3171 (2004)
• Bassand, J., et al.: Eur. Heart J., 28, 1598 (2004)
• Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2004)