Tiazofurin

• 产品号: T437200
• CAS号: 60084-10-8
• 分子式: C9H12N2O5S
• 分子量: 260.26698

产品别名

• 标题: Tiazofurin
• IUPAC标准名: 2-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
• IUPAC传统名: 2-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
• 别名: NSC 286193; Riboxamide; NSC 286-193; 2-β-D-Ribofuranosylthiazole-4-carboxamide; Tiazofurine; 2-β-D-Ribofuranosyl-4-thiazolecarboxamide; CI 909; TCAR

产品登记号

• CAS号: 60084-10-8

产品详细信息

详细说明 (English)

Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5'-monophosphate (IMP) dehydrogenase.

参考文献

• Streeter, D.G. et al.: Biochem. Biophys. Res. Comm., 115, 544 (1983)
• Boritzki, T. et al.: Biochem. Pharmacol., 34, 1109 (1983)
• Malek, K. et al.: Leuk. Res., 28, 1125 (1983)