Thiostrepton

• 产品号: T375150
• CAS号: 1393-48-2
• 分子式: C72H85N19O18S5
• 分子量: 1664.8868
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Thiostrepton
• IUPAC标准名: 2-({2-[(1R,8S,11Z,18S,25S,26R,37R,40S,46S,53S,59S)-37-[(2S)-butan-2-yl]-18-[(2S,3R)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[(1R)-1-hydroxyethyl]-60-[(1S)-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.2^2^9,^3^2.1^2,^5.1^1^2,^1^5.1^1^9,^2^2.1^3^1,^3^5.1^5^4,^5^7.0^1,^5^3]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazol-4-yl}formamido)-N-(1-carbamoyleth-1-en-1-yl)prop-2-enamide
• IUPAC传统名: 2-({2-[(1R,8S,11Z,18S,25S,26R,37R,40S,46S,53S,59S)-37-[(2S)-butan-2-yl]-18-[(2S,3R)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[(1R)-1-hydroxyethyl]-60-[(1S)-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.2^2^9,^3^2.1^2,^5.1^1^2,^1^5.1^1^9,^2^2.1^3^1,^3^5.1^5^4,^5^7.0^1,^5^3]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazol-4-yl}formamido)-N-(1-carbamoyleth-1-en-1-yl)prop-2-enamide

产品登记号

• CAS号: 1393-48-2

产品性质

• 外观: Off-White Solid
• 熔点: 248-257°C (dec.)
• 溶解度: Chloroform
• 溶解度: Acetic Acid
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Natural antibiotic derived from Streptomyces.

参考文献

• Starosta, A., et al.; Chem. Biol., 16, 1087 (2009)
• Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2009)
• Kwok, J., et al.: Mol. Cancer Res., 8, 24 (2009)