Tezosentan-d4

• 产品号: T321502
• 分子式: C27H27N9O6S
• 分子量: 605.62498

产品别名

• 标题: Tezosentan-d4
• IUPAC标准名: N-{6-[2-hydroxy(^2H₄)ethoxy]-5-(2-methoxyphenoxy)-2-[2-(1H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl}-5-(propan-2-yl)pyridine-2-sulfonamide
• IUPAC传统名: N-{6-[2-hydroxy(^2H₄)ethoxy]-5-(2-methoxyphenoxy)-2-[2-(1H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl}-5-isopropylpyridine-2-sulfonamide
• 别名: N-[6-(2-Hydroxyethoxy-d4)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-2-pyridinesulfonamide

产品详细信息

详细说明 (English)

Labelled Tezosentan (T321502). A potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan (B675900). It is used in the treatment of congestive heart failure.

参考文献

• lozel, M., et al.: J. Pharmacol. Exp. Ther., 290, 840 (1999)
• Dingemanse, J., et al.: Br. J. Clin. Pharmacol., 53, 355 (1999)
• Schalcher, C., et al.: Am. Heart J., 142, 340 (1999)