3α,5α-Tetrahydronorethisterone

• 产品号: T294135
• CAS号: 16392-60-2
• 分子式: C20H30O2
• 分子量: 302.451

产品别名

• 标题: 3α,5α-Tetrahydronorethisterone
• IUPAC标准名: (1R,2S,5R,7S,10R,11S,14R,15S)-14-ethynyl-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecane-5,14-diol
• IUPAC传统名: (1R,2S,5R,7S,10R,11S,14R,15S)-14-ethynyl-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecane-5,14-diol
• 别名: (3α,5α,17α)-19-Norpregn-20-yne-3,17-diol; 19-Nor-5α,17α-pregn-20-yne-3α,17-diol; 17α-Ethynyl-5α-oestrane-3α,17β-diol; 17α-Ethynyl-5α-estrane-3α,17β-diol

产品登记号

• CAS号: 16392-60-2

产品详细信息

详细说明 (English)

A 3α-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as a estrogen receptor in osteoblastic cells. It also has novel nongenomic endothelium-independent vasorelaxing effects.

参考文献

• Lemus, A.E. et al.: J. Endocrinol., 200, 199 (2009)
• Perusquia, M. et al.: Eur. J. Pharmacol., 475, 161 (2009)
• Blom, M.J. et al.: Drug Metab. Disp., 29, 976 (2009)