Tenofovir-d5

• 产品号: T018503
• 分子式: C9H14N5O4P
• 分子量: 287.212321

产品别名

• 标题: Tenofovir-d5
• IUPAC标准名: ({[(2S)-1-(6-amino-9H-purin-9-yl)(1,1,3,3,3-^2H₅)propan-2-yl]oxy}methyl)phosphonic acid
• IUPAC传统名: {[(2S)-1-(6-aminopurin-9-yl)(1,1,3,3,3-^2H₅)propan-2-yl]oxy}methylphosphonic acid
• 别名: (R)-PMPA-d5; (R)-9-(2-Phosphonomethoxypropyl)adenine-d5; [(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy-d5]methyl]phosphonic Acid; GS-1278-d5

产品详细信息

详细说明 (English)

Labelled Tenofovir (T018500). Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.

参考文献

• Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997)
• Wyles, D., et al.: Clin Infect. Dis., 40, 174 (1997)
• Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (1997)
• Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (1997)