TelavancinDISCONTINUED

• 产品号: T015800
• CAS号: 372151-71-8
• 分子式: C80H106Cl2N11O27P
• 分子量: 1755.634901

产品别名

• 标题: TelavancinDISCONTINUED
• IUPAC标准名: (1S,2R,18R,22S,25R,28R,40S)-22-(carbamoylmethyl)-47,49-dichloro-48-{[(2S,3R,4S,6R)-3-{[(2S,4S,5S,6S)-4-{[2-(decylamino)ethyl]amino}-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-36-{[(phosphonomethyl)amino]methyl}-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^3,^6.2^1^4,^1^7.1^8,^1^2.1^2^9,^3^3.0^1^0,^2^5.0^3^4,^3^9]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid
• IUPAC传统名: (1S,2R,18R,22S,25R,28R,40S)-22-(carbamoylmethyl)-47,49-dichloro-48-{[(2S,3R,4S,6R)-3-{[(2S,4S,5S,6S)-4-{[2-(decylamino)ethyl]amino}-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-36-{[(phosphonomethyl)amino]methyl}-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^3,^6.2^1^4,^1^7.1^8,^1^2.1^2^9,^3^3.0^1^0,^2^5.0^3^4,^3^9]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid
• 别名: Arbelic; N3''-[2-(Decylamino)ethyl]-29-[[(phosphonomethyl)amino]methyl]vancomycin

产品登记号

• CAS号: 372151-71-8

产品详细信息

详细说明 (English)

Broad spectrum, semi-synthetic glycopeptide antibiotic; inhibits bacterial cell wall formation and disrupts cell membrane integrity. Antibacterial.

参考文献

• Judice, J.K., et al.: Bioorg. Med. Chem. Lett., 13, 4165 (2003)
• King, A., et al.: J. Antimicrob. Chemother., 53, 797 (2003)
• Stryjewski, M.E., et al.: Clin. Infect. Dis., 40, 1601 (2003)