Tazarotene-d8

• 产品号: T010052
• 分子式: C21H21NO2S
• 分子量: 351.46194
• 保 存: Refrigerator

产品别名

• 标题: Tazarotene-d8
• IUPAC标准名: ethyl 6-{2-[4,4-bis(^2H₃)methyl-3,4-dihydro-2H-1-benzothiopyran-6-yl]ethynyl}pyridine-3-carboxylate
• IUPAC传统名: ethyl 6-{2-[4,4-bis(^2H₃)methyl-2,3-dihydro-1-benzothiopyran-6-yl]ethynyl}pyridine-3-carboxylate
• 别名: Zorac-d8; Tazorac-d8; 6-[2-(3,4-Dihydro-4,4-(dimethyl-d6)-2H-1-benzothiopyran-6-yl-d2)ethynyl]-3-pyridinecarboxylic Acid Ethyl Ester; AGN 190168-d8

产品性质

• 外观: Light Brown Solid
• 熔点: 103-104°C
• 溶解度: DMSO
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Labelled Tazarotene (T010050). An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.

参考文献

• Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999)
• Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (1999)