Taurodeoxycholic-2,2,3,4,4-d5 Acid (d5 major)

• 产品号: T009002
• 分子式: C26H45NO6S
• 分子量: 499.7036
• 保 存: Refrigerator

产品别名

• 标题: Taurodeoxycholic-2,2,3,4,4-d5 Acid (d5 major)
• IUPAC标准名: 2-[(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
• IUPAC传统名: 2-[(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethanesulfonic acid
• 别名: 2-[[(3α,5β,12β)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid-d5; Deoxytaurocholic-d5 Acid; Taurodesoxycholic-d5 Acid; Tudcabil-d5; N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)taurine-d5; Deoxycholyltaurine-d5

产品性质

• 外观: White Solid
• 熔点: >170°C (dec.)
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

参考文献

• Cheng, K., et al.: Biochem. J., 330, 353 (1998)
• Cheng, K., et al.: Cancer Res., 63, 6744 (1998)
• Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (1998)
• Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (1998)
• Fang, D., et al.: J. Biol. Chem., 282, 11221