Sunitinib-d10

• 产品号: S820002
• 分子式: C22H27FN4O2
• 分子量: 398.4737832
• 保 存: -20°C Freezer

产品别名

• 标题: Sunitinib-d10
• IUPAC标准名: N-{2-[bis(^2H₅)ethylamino]ethyl}-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide
• IUPAC传统名: N-{2-[bis(^2H₅)ethylamino]ethyl}-5-{[(3Z)-5-fluoro-2-oxo-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide
• 别名: N-[2-(Diethyl-d10)aminoethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; Sutent-d10; SU-11248-d10

产品性质

• 外观: Yellow Solid
• 熔点: >210°C
• 溶解度: Dichloromethane
• 溶解度: Methanol
• 保存条件: -20°C Freezer
• 保存注意事项: Light and Temperature Sensitive

产品详细信息

详细说明 (English)

Labelled Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK).

参考文献

• Sun, L., et al.: J. Med. Chem., 46, 1116 (2003)
• Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003)
• Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2003)
• Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2003)