N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester 1,4- Dioxane complex

• 产品号: S689850
• CAS号: 1215667-16-5
• 分子式: C16H21N3O10
• 分子量: 415.35204
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester 1,4- Dioxane complex
• IUPAC标准名: 1,4-dioxane 2,5-dioxopyrrolidin-1-yl 3-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}amino)propanoate
• IUPAC传统名: dioxane 2,5-dioxopyrrolidin-1-yl 3-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}amino)propanoate
• 别名: N-[[N-[(Succinimidooxy)carbonyl]-β-alanyl]oxy]succinimide 1,4- Dioxane

产品登记号

• CAS号: 1215667-16-5

产品性质

• 外观: White Solid
• 熔点: 163-164°C
• 溶解度: DMSO
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A short, amino reactive homobifunctional crosslinking reagent. Crosslinking distance 8.3 Å. It is useful in polymer coupling to proteins, because it may lead to a better selectivity among all the amino groups present in a protein, thus yielding less heterogeneous PEG-protein conjugates mixture because only the most nucleophilic and solvent exposed amines can react.

参考文献

• Gross, H., et al.: Tetrahedron, 24, 6935 (1968)
• Clark, R., et al.: J. Biol. Chem., 271, 21969 (1968)
• Guiotto, A., et al.: Bioorg. Med. Chem., 12, 5031 (1968)