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STn Epitope N-Acetate

产品号 S687050 公司名称 Toronto Research Chemicals
CAS号 385398-89-0 公司网站 http://www.trc-canada.com
分子式 C24H39N3O17 电 话 +1 (416) 665-9696
分子量 641.57636 传 真 +1 (416) 665-4439
纯 度 电子邮件 info@trc-canada.com
保 存 Chembase数据库ID: 177884

产品价格信息

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产品别名

标题
STn Epitope N-Acetate
IUPAC标准名
(2R,4S,5R,6R)-2-{[(2R,3R,4R,5R,6S)-6-[(2S)-2-carboxy-2-acetamidoethoxy]-5-acetamido-3,4-dihydroxyoxan-2-yl]methoxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
IUPAC传统名
(2R,4S,5R,6R)-2-{[(2R,3R,4R,5R,6S)-6-[(2S)-2-carboxy-2-acetamidoethoxy]-5-acetamido-3,4-dihydroxyoxan-2-yl]methoxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
别名
6-O-α-Sialyl-2-acetamido-2-deoxy-α-D-galactopyranosyl-1-O-L-serine N-Acetate
N-Acetyl-O-[2-(acetylamino)-6-O-(N-acetyl-α-neuraminosyl)-2-deoxy-α-D-galactopyranosyl]-L-serine

产品登记号

CAS号 385398-89-0

产品性质

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外观 Off-White Amorphous Solid
溶解度 Warm Methanol
溶解度 Water
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保存注意事项 Moisture Sensitive

产品详细信息

详细说明 (English)
Sialosyl-Tn epitope is a cancer associated carbohydrate antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. These antigens appear as clusters of glycopeptide repea

参考文献

  • Kim, J.M., and Roy, R.: Tetrahedron Lett., 38, 3487 (1997)
  • Qiu, D., and Koganty, R.: Tetrahedron Lett., 38, 961 (1997)
  • Toyokuni, T., and Singhal, A.K.: Chem. Soc. Rev., 231, (1995)