SN-38 Glucuronide

• 产品号: S589980
• CAS号: 121080-63-5
• 分子式: C28H28N2O11
• 分子量: 568.52872
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: SN-38 Glucuronide
• IUPAC标准名: (2S,3S,4S,5R,6R)-6-{[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC传统名: (2S,3S,4S,5R,6R)-6-{[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• 别名: 4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl β-D-Glucopyranosiduronic Acid; (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl β-D-Glucopyranosiduronic Acid

产品登记号

• CAS号: 121080-63-5

产品性质

• 外观: Pale Yellow Solid
• 熔点: >250°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A metabolite of Irinotecan

参考文献

• Fujita, K., et al.: Biol. Pharm. Bull., 31, 2137 (2008)
• Sandanaraj, E., et al.: Pharmacogen. J., 8, 174 (2008)
• Chen, K., et al.: Chem. Biol., 15, 1277 (2008)
• Prijovich, Z., et al.: Mol. Canc. Ther., 8, 940 (2008)