Sitaxsentan-13C4 Sodium

• 产品号: S493502
• 分子式: C18H14ClN2NaO6S2
• 分子量: 480.85694935

产品别名

• 标题: Sitaxsentan-13C4 Sodium
• IUPAC标准名: sodium 1-[3-({[4-chloro-3-(^1^3C)methyl(3,4,5-^1^3C₃)-1,2-oxazol-5-yl]azanidyl}sulfonyl)thiophen-2-yl]-2-(6-methyl-2H-1,3-benzodioxol-5-yl)ethan-1-one
• IUPAC传统名: sodium 1-(3-{[4-chloro-3-(^1^3C)methyl(3,4,5-^1^3C₃)-1,2-oxazol-5-yl]azanidylsulfonyl}thiophen-2-yl)-2-(6-methyl-2H-1,3-benzodioxol-5-yl)ethanone
• 别名: Thelin-13C4; TBC 11251-13C4; IPI 1040-13C4; Sitaxentan-13C4 Sodium; N-(4-Chloro-3-methyl-5-isoxazolyl-13C4)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide Sodium; Sitax-13C4

产品详细信息

详细说明 (English)

Labelled Sitaxsentan. Selective endothelin A (ETA) receptor antagonist. Antihypertensive. Used in treatment of chronic heart failure.

参考文献

• Wu, C., et al.: J. Med. Chem., 40, 1690 (1997)
• Tilton, R.G., et al.: Pulm. Pharmacol. Ther., 13, 87 (1997)
• Horn, E.M., et al.: Expert. Opin. Invest. Drugs, 13, 1483 (1997)
• Langleben, D., et al.: Chest, 126, 1377 (1997)