Sitaxsentan Sodium

• 产品号: S493500
• CAS号: 210421-74-2
• 分子式: C18H14ClN2NaO6S2
• 分子量: 476.88633

产品别名

• 标题: Sitaxsentan Sodium
• IUPAC标准名: sodium 1-(3-{[(4-chloro-3-methyl-1,2-oxazol-5-yl)azanidyl]sulfonyl}thiophen-2-yl)-2-(6-methyl-2H-1,3-benzodioxol-5-yl)ethan-1-one
• IUPAC传统名: sodium 1-{3-[(4-chloro-3-methyl-1,2-oxazol-5-yl)azanidylsulfonyl]thiophen-2-yl}-2-(6-methyl-2H-1,3-benzodioxol-5-yl)ethanone
• 别名: Sitax; TBC 11251; IPI 1040; N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide Sodium; Sitaxentan Sodium; Thelin

产品登记号

• CAS号: 210421-74-2

产品详细信息

详细说明 (English)

Selective endothelin A (ETA) receptor antagonist. Antihypertensive. Used in treatment of chronic heart failure.

参考文献

• Wu, C., et al.: J. Med. Chem., 40, 1690 (1997)
• Tilton, R.G., et al.: Pulm. Pharmacol. Ther., 13, 87 (1997)
• Horn, E.M., et al.: Expert. Opin. Invest. Drugs, 13, 1483 (1997)
• Langleben, D., et al.: Chest, 126, 1377 (1997)