Sitagliptin Phosphate

• 产品号: S491000
• CAS号: 654671-78-0
• 分子式: C16H16F6N5O5P
• 分子量: 503.2929202
• 保 存: -20°C Freezer

产品别名

• 标题: Sitagliptin Phosphate
• IUPAC标准名: (3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphoperoxol hydrogen
• IUPAC传统名: phosphoperoxol sitagliptin hydrogen
• 别名: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate

产品登记号

• CAS号: 654671-78-0

产品性质

• 外观: White Solid
• 熔点: 202-204°C
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

参考文献

• Kim, D., et al.: J. Med. Chem. 48, 141 (2005)
• Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005)
• Bergman, A., et al: Clin. Ther. 28, 55 (2006)