Sitagliptin Carbamoyl β-D-Glucuronide

• 产品号: S490995
• CAS号: 940002-59-5
• 分子式: C23H23F6N5O9
• 分子量: 627.4472392
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Sitagliptin Carbamoyl β-D-Glucuronide
• IUPAC标准名: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({[(2R)-4-oxo-4-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamoyl}oxy)oxane-2-carboxylic acid
• IUPAC传统名: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-({[(2R)-4-oxo-4-[3-(trifluoromethyl)-5H,6H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamoyl}oxy)oxane-2-carboxylic acid
• 别名: 1-[N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]carbamate] β-D-Glucopyranuronic Acid

产品登记号

• CAS号: 940002-59-5

产品性质

• 外观: White Solid
• 熔点: 167-169°C (dec.)
• 溶解度: Methanol
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A metabolite of Sitagliptin.

参考文献

• Zander, M., et al.: Lancet, 359, 824 (2002)
• Kim, D., et al.: J. Med. Chem., 48, 141 (2002)
• Bergman, A., et al.: Clin. Ther., 28, 55 (2002)
• Drucker, D., et al.: Cell Metab., 3, 153 (2002)
• Vincent, S., et al.: Drug Metab. Dispos., 35 (2002)