Simvastatin-d6 Hydroxy Acid Ammonium Salt

• 产品号: S485022
• 分子式: C25H43NO6
• 分子量: 453.61202
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Simvastatin-d6 Hydroxy Acid Ammonium Salt
• IUPAC标准名: ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-{[2,2-bis(^2H₃)methylbutanoyl]oxy}-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC传统名: ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-{[2,2-bis(^2H₃)methylbutanoyl]oxy}-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• 别名: (βR,δR,1S,2S,6R,8S,8aR)-8-[2,2-(Dimethyl-d6)-1-oxobutoxy]-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Ammonium Salt; Simvastatin-d6 Ammonium Salt; Simvastatin-d6 Carboxylic Acid Ammonium Salt; Simvastatin-d6 Acid Ammonium Salt

产品性质

• 外观: White to Off-White Solid
• 熔点: 150-153°C
• 溶解度: DMSO
• 溶解度: Ethanol
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A deuterated metabolite of Simvastin (S485000). A competitive inhibitor of HMG-CoA reductase.

参考文献

• Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986)
• Mol, M.J., et al.: Lancet, 2, 936 (1986)