Simvastatin Hydroxy Acid Ammonium Salt

• 产品号: S485020
• CAS号: 139893-43-9
• 分子式: C25H43NO6
• 分子量: 453.61202
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Simvastatin Hydroxy Acid Ammonium Salt
• IUPAC标准名: ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC传统名: ammonium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• 别名: Simvastatin Ammonium Salt; (βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Ammonium Salt; Simvastatin Carboxylic Acid Ammonium Salt; Simvastatin Acid Ammonium Salt

产品登记号

• CAS号: 139893-43-9

产品性质

• 外观: White Solid
• 熔点: 128-131°C
• 溶解度: DMSO
• 溶解度: Ethanol
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A metabolite of Simvastin (S485000). A competitive inhibitor of HMG-CoA reductase.

参考文献

• Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986)
• Mol, M.J., et al.: Lancet, 2, 936 (1986)