Simvastatin-d6

• 产品号: S485002
• 分子式: C25H38O5
• 分子量: 418.56622
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Simvastatin-d6
• IUPAC标准名: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-bis(^2H₃)methylbutanoate
• IUPAC传统名: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-bis(^2H₃)methylbutanoate
• 别名: Cholestat-d6; Novo-Simvastatin-d6; Sinvacor-d6; Statin-d6; Zocor-d6; 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; (+)-Simvastatin-d6; Lipex-d6; Simvotin-d6; Zorced-d6

产品性质

• 外观: White Solid
• 熔点: 117-120°C
• 溶解度: Dichloromethane
• 溶解度: DMF
• 溶解度: DMSO
• 溶解度: Ether
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: -20°C Freezer, Under Inert Atmosphere
• 保存注意事项: Hygroscopic

产品详细信息

详细说明 (English)

Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic.

参考文献

• Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986)
• Mol, M.J., et al.: Lancet, 2, 936 (1986)