Ruboxistaurin-d6 Hydrochloride

• 产品号: R701527
• 分子式: C28H29ClN4O3
• 分子量: 505.00786

产品别名

• 标题: Ruboxistaurin-d6 Hydrochloride
• IUPAC标准名: (18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^7,^1^4.0^2,^6.0^8,^1^3.0^2^2,^2^7]nonacosa-1(28),2(6),7(29),8,10,12,22,24,26-nonaene-3,5-dione hydrochloride
• IUPAC传统名: ruboxistaurin hydrochloride
• 别名: (9S)-9-[[(Dimethyl-d6)amino]methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride; LY 333531-d6

产品详细信息

详细说明 (English)

Labelled Ruboxistaurin. Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin

参考文献

• Miller, J. et al.: Diabetes Metab. Rev., 13, 37 (1997)
• Suzuma, I. et al.: J. Biol. Chem., 277, 1047 (1997)
• ;Ali, N. et al.: J. Pharmacol. Sci., 98, 130 (1997)