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Ruboxistaurin Hydrochloride

产品号 R701525 公司名称 Toronto Research Chemicals
CAS号 169939-93-9 公司网站 http://www.trc-canada.com
分子式 C20H15N3O6 电 话 +1 (416) 665-9696
分子量 393.3496 传 真 +1 (416) 665-4439
纯 度 电子邮件 info@trc-canada.com
保 存 Chembase数据库ID: 154370

产品价格信息

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产品别名

标题
Ruboxistaurin Hydrochloride
IUPAC标准名
(19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
IUPAC传统名
(19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
别名
(9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride
LY 333531

产品登记号

CAS号 169939-93-9

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产品详细信息

详细说明 (English)
Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of

参考文献

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  • Ali, N., et al.: J. Pharmacol. Sci., 98, 130 (1997)