Sch 58053

• 产品号: S199950
• CAS号: 194423-53-5
• 分子式: C26H23ClFNO3
• 分子量: 451.9171232
• 保 存: -20°C Freezer

产品别名

• 标题: Sch 58053
• IUPAC标准名: (3R,4s,7S)-7-(4-chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-3-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-1-one
• IUPAC传统名: (3R,4s,7S)-7-(4-chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-3-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-1-one
• 别名: (3R,4β,7α)-7-(4-Chlorophenyl)-2-(4-fluorophenyl)-7-hydroxy-3-(4-hydroxyphenyl)-2-azaspiro[3.5]nonan-1-one

产品登记号

• CAS号: 194423-53-5

产品性质

• 外观: White Solid
• 熔点: 211-213°C
• 溶解度: DMSO
• 溶解度: Ethanol
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

An analog of Ezetimibe (E975000). SCH 58053 is a potent, rapid, and selective inhibitor of lymphatic cholesterol transport in the intestine.

参考文献

• Ly, H., et al.: Biochem. J., 286, 937 (1992)
• Dujovne, C., et al.: Am. J. Cardiol., 90, 1092 (1992)
• Repa, J., et al.: J. Lipid Res., 43, 1864 (1992)
• Knopp, R., et al.: Eur. Heart J., 24, 729 (1992)
• Altmann, S., et al.: Science, 303, 1201 (1992)