SB 612111 Hydrochloride

• 产品号: S154750
• 分子式: C24H30Cl3NO
• 分子量: 454.8601

产品别名

• 标题: SB 612111 Hydrochloride
• IUPAC标准名: (5S,7S)-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol hydrochloride
• IUPAC传统名: (5S,7S)-7-{[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl}-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol hydrochloride
• 别名: (5S,7S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol Hydrochloride; (-)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol Hydrochloride

产品详细信息

详细说明 (English)

A selective nociceptin/orphanin FQ receptor antagonist. A potentially useful adjunct to chronic pain therapy with opioids and can be used to treat conditions in which thermal hyperalgesia is a significant component of the pain response.

参考文献

• Rizzi, A. et al.: J. Pharmacol. Exp. Therap., 321, 968 (2007)
• Liao, Y. et al.: Eur. J. Pharmacol., 657, 84 (2007)
• Zaratin. P.F. et al.: J. Pharmacol. Exp. Therap., 308, 454 (2007)