Roflumilast-d4

• 产品号: R639702
• 分子式: C17H14Cl2F2N2O3
• 分子量: 403.2074664
• 保 存: -20°C Freezer

产品别名

• 标题: Roflumilast-d4
• IUPAC标准名: 3-[(2,2,3,3-^2H₄)cyclopropylmethoxy]-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
• IUPAC传统名: 3-[(2,2,3,3-^2H₄)cyclopropylmethoxy]-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
• 别名: Daxas-d4; BYK 20869-d4; 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d4; BY 217-d4

产品性质

• 保存条件: -20°C Freezer
• 外观: White Solid
• 熔点: 156-158°C
• 溶解度: DMSO
• 溶解度: Methanol

产品详细信息

详细说明 (English)

Labelled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease.

参考文献

• Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001)
• Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001)
• Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2001)
• Rabe, K.F., et al.: Lancet, 366, 563 (2001)