Ritonavir-d6

• 产品号: R535002
• 分子式: C37H48N6O5S2
• 分子量: 720.94422
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Ritonavir-d6
• IUPAC标准名: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({2-[(1,1,1,3,3,3-^2H₆)propan-2-yl]-1,3-thiazol-4-yl}methyl)carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
• IUPAC传统名: 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({2-[(1,1,1,3,3,3-^2H₆)propan-2-yl]-1,3-thiazol-4-yl}methyl)carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
• 别名: Norvir-d6; ABT 538-d6; A 84538-d6; (3S,4S,6S,9S)-4-Hydroxy-12-methyl-9-(1-methylethyl-d6)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-thiazolylmethyl Ester

产品性质

• 外观: Off-White Solid
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A deuterated selective HIV protease inhibitor Ritonavir (R535000).

参考文献

• Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994)
• Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (1994)
• Harrigan, P., et al.: J. Infect. Dis., 191, 339 (1994)
• Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)