Prostratin

• 产品号: P838800
• CAS号: 60857-08-1
• 分子式: C22H30O6
• 分子量: 390.47

产品别名

• 标题: Prostratin
• IUPAC标准名: (1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-13-yl acetate
• IUPAC传统名: prostratin
• 别名: 12-Deoxyphorbol 13-acetate; (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one; Stillingia Factor S7; NSC 623310; 13-O-Acetylphorbol

产品登记号

• CAS号: 60857-08-1

产品详细信息

详细说明 (English)

It is a protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). Research indicated that prostratin has potential to be useful in the treatment of HIV as it flushes viral reservoirs in latently infecte

参考文献

• Reuben, et al.: Clin. Cancer Res., 6, 1671 (2000)
• Korin, Y., et al.: J. Virol., 76, 8118 (2000)
• Wei, X., et al.: Nature, 422, 307 (2000)
• Kutsch, O., et al.: Antimicrob. Agents Chemother., 48, 1652 (2000)