Pravastatin-d3 Sodium Salt

• 产品号: P702002
• 分子式: C23H35NaO7
• 分子量: 446.50957
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Pravastatin-d3 Sodium Salt
• IUPAC标准名: sodium (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2R)-2-(^2H₃)methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC传统名: sodium (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2R)-2-(^2H₃)methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• 别名: Mevalotin-d3; βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-(methyl-d3)-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt; Pravaselect-d3; Pravachol-d3; Elisor-d3; Kopostat-d3

产品性质

• 外观: White Solid
• 熔点: 160-164°C (dec.)
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A stable isotope of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of Mevastatin.A representative lot is 86% d3, 13% d2 and 1% d1.

参考文献

• Serizawa, N., et al.: J. Antibiot., 36, 604 (1983)
• Yoshino, G., et al.: Lancet, 2, 740 (1983)
• White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)