Pimecrolimus

• 产品号: P445000
• CAS号: 137071-32-0
• 分子式: C43H68ClNO11
• 分子量: 810.45312
• 保 存: -20°C Freezer

产品别名

• 标题: Pimecrolimus
• IUPAC标准名: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25R,27R)-12-[(1E)-1-[(1R,3S,4S)-4-chloro-3-methoxycyclohexyl]prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0^4,^9]octacos-18-ene-2,3,10,16-tetrone
• IUPAC传统名: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25R,27R)-12-[(1E)-1-[(1R,3S,4S)-4-chloro-3-methoxycyclohexyl]prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0^4,^9]octacos-18-ene-2,3,10,16-tetrone
• 别名: SDZ-ASM 981; Picrolimus; 33-epi-Chloro-33-desoxyascomycin; Elidel; 33-Epichloro-33-desoxyascomycin; ASM 981

产品登记号

• CAS号: 137071-32-0

产品性质

• 外观: White Solid
• 熔点: 142-144°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Macrolactam ascomycin derivative; inhibits production of pro-inflammatory cytokines by T cells and mast cells. Immunosuppresant.

参考文献

• Gassberger, M., et al.: Br. J. Dermatol., 141, 264 (1999)
• Queille-Roussel, C., et al.: Contact Dermatitis, 42, 349 (1999)