PF-573228

• 产品号: P293950
• CAS号: 869288-64-2
• 分子式: C22H20F3N5O3S
• 分子量: 491.4861096
• 保 存: Refrigerator

产品别名

• 标题: PF-573228
• IUPAC标准名: 6-[(4-{[(3-methanesulfonylphenyl)methyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl)amino]-1,2,3,4-tetrahydroquinolin-2-one
• IUPAC传统名: 6-[(4-{[(3-methanesulfonylphenyl)methyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl)amino]-3,4-dihydro-1H-quinolin-2-one
• 别名: PF 573228; 6-[(4-((3-(Methanesulfonyl)benzyl)amino)-5-trifluoromethylpyrimidin-2-yl)amino]-3,4-dihydro-1H-quinolin-2-one; 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone

产品登记号

• CAS号: 869288-64-2

产品性质

• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A novel focal adhesion kinase inhibitor that has been shown to suppress the adverse phenotype of endocrine-resistant breast cancer cells and improve endocrine response in endocrine-sensitive cells.

参考文献

• Slack-Davis, J.K. et al.: J. Biol. Chem., 282, 14845 (2007)
• Hiscox, S. et al.: Breast Cancer Res. Treat., 125, 659 (2007)