Perphenazine

• 产品号: P291100
• CAS号: 58-39-9
• 分子式: C21H28O4
• 分子量: 344.44462
• 保 存: Refrigerator

产品别名

• 标题: Perphenazine
• IUPAC标准名: (1S,2S,9R,10S,11S,14R,15S)-14-ethynyl-2-hydroperoxy-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC传统名: (1S,2S,9R,10S,11S,14R,15S)-14-ethynyl-2-hydroperoxy-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• 别名: 1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine; Chloriprozine; Thilatazin; Tranquisan; Fluphenazine Imp. E (Pharmeuropa); 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol; Chlorperphenazine; Decentan; Emesinal; Etaperazin; Perfenil; Perphenan; Perphenazin; Sch 3940; Trifaron

产品登记号

• CAS号: 58-39-9

产品性质

• 外观: Off-White to Pale Yellow Solid
• 熔点: 95-98°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.

参考文献

• Gaertner, H.J., et al.: Drug Metab. Dispos., 3, 437 (1975)
• O Brien, S., et al.: J. Med. Chem., 48, 1287 (1975)
• Briggs, K., et al.: Toxicology, 231, 113 (1975)
• Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (1975)