Peplomycin Sulfate

• 产品号: P285250
• CAS号: 70384-29-1
• 分子式: C61H90N18O25S3
• 分子量: 1571.6679

产品别名

• 标题: Peplomycin Sulfate
• IUPAC标准名: sulfuric acid (2R,3S,4S,5R,6R)-2-{[(2R,3S,4S,5S,6S)-2-{2-[(6-amino-2-{1-[(2-amino-2-carbamoylethyl)amino]-2-carbamoylethyl}-5-methylpyrimidin-4-yl)formamido]-2-({3-hydroxy-4-[(2-hydroxy-1-{[2-(4-{4-[(3-{[(1R)-1-phenylethyl]amino}propyl)carbamoyl]-1,3-thiazol-2-yl}-1,3-thiazol-2-yl)ethyl]carbamoyl}propyl)carbamoyl]-4-methylbutan-2-yl}carbamoyl)-1-(1H-imidazol-4-yl)ethoxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl carbamate
• IUPAC传统名: sulfuric acid (2R,3S,4S,5R,6R)-2-{[(2R,3S,4S,5S,6S)-2-{2-[(6-amino-2-{1-[(2-amino-2-carbamoylethyl)amino]-2-carbamoylethyl}-5-methylpyrimidin-4-yl)formamido]-2-({3-hydroxy-4-[(2-hydroxy-1-{[2-(4-{4-[(3-{[(1R)-1-phenylethyl]amino}propyl)carbamoyl]-1,3-thiazol-2-yl}-1,3-thiazol-2-yl)ethyl]carbamoyl}propyl)carbamoyl]-4-methylbutan-2-yl}carbamoyl)-1-(1H-imidazol-4-yl)ethoxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl carbamate
• 别名: N1-[3-[[(1S)-1-phenylethyl]amino]propyl]bleomycinamide Sulfate; Pepleo; NK 631; Pepleomycin Sulfate

产品登记号

• CAS号: 70384-29-1

产品性质

• 外观: Pale Yellow Amorphous Powder
• 熔点: 196-198°C
• 溶解度: DMSO
• 溶解度: DMF
• 溶解度: Methanol
• 溶解度: Water

产品详细信息

详细说明 (English)

A derivative of Bleomycin with cytostatic activity and less pulmonary toxicity than the natural Bleomycin mixture.

参考文献

• Takahashi, K., et al.: J. Antibiot., 32, 36 (1979)
• Sikic, B.I., et al.: Cancer Treat. Rep., 64, 659 (1979)