Pentostatin

• 产品号: P227350
• CAS号: 53910-25-1
• 分子式: C11H16N4O4
• 分子量: 268.26914
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Pentostatin
• IUPAC标准名: (8R)-3-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8-ol
• IUPAC传统名: (8R)-3-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8-ol
• 别名: PD-ADI; (8R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-imidazo[4,5-d][1,3]diazepin-8-ol; 2'-DCF; 2'-Deoxycoformycin; Coforin; (R)-; CI 825; CL 67310465; Cl 825; Co-V; Co-Vidarabine; NSC 218321; NSC 247520; Nipent; Vira A Deaminase Inhibitor

产品登记号

• CAS号: 53910-25-1

产品性质

• 外观: White Solid
• 熔点: 225-227°C
• 溶解度: DMSO
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.

参考文献

• Rogler-Brown, T. et al.: Biochem. Pharmacol., 28, 201 (1979)
• Johnston, J.B. et al.: J. Natl. Canvcer Inst., 80, 765 (1979)
• Fortune, A.F. et al.: Leuk. and Lymph., 51, 839 (1979)
• Robak, T. et al.: Drugs, 69, 2415 (1979)