Pemetrexed Disodium

• 产品号: P219500
• CAS号: 150399-23-8
• 分子式: C20H19N5Na2O6
• 分子量: 471.3743
• 保 存: -20°C Freezer

产品别名

• 标题: Pemetrexed Disodium
• IUPAC标准名: disodium (2R)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate
• IUPAC传统名: disodium (2R)-2-{[4-(2-{2-amino-4-oxo-1H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioate
• 别名: Pemetrexed Sodium; Alimta; N-[4-[(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium; LY 231514; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Sodium Salt; LY 231514 Disodium; Rolazar; Tifolar

产品登记号

• CAS号: 150399-23-8

产品性质

• 外观: Off-White Solid
• 熔点: 254-258°C (dec.)
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic.

参考文献

• McDonald, A.C., et al.: Clin. Cancer Res., 4, 605 (1998)
• John, W., et al.: Cancer, 88, 1807 (1998)
• Miller, K.D., et al.: Ann. Oncol., 11, 101 (1998)