PD-161570

• 产品号: P217490
• CAS号: 192705-80-9
• 分子式: C26H35Cl2N7O
• 分子量: 532.5084
• 保 存: Refrigerator

产品别名

• 标题: PD-161570
• IUPAC标准名: 3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[4-(diethylamino)butyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea
• IUPAC传统名: 3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[4-(diethylamino)butyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea
• 别名: 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea; N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea

产品登记号

• CAS号: 192705-80-9

产品性质

• 外观: Off-White Solid
• 熔点: 215-230°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells.

参考文献

• Batley, B.L. et al.: Life Sci., 62, 143 (1997)
• Hamby, J.M. et al.: J. Med. Chem., 40, 2296 (1997)
• Nandi, S. et al.: J. Enz. Inhib. Med. Chem., 24, 937 (1997)