(S,S)-Palonosetron-d3 Hydrochloride

• 产品号: P165802
• 分子式: C19H25ClN2O
• 分子量: 332.8676
• 保 存: Refrigerator

产品别名

• 标题: (S,S)-Palonosetron-d3 Hydrochloride
• IUPAC标准名: (5S)-3-[(3S)-(3-^2H)-1-azabicyclo[2.2.2]octan-3-yl](4,4-^2H₂)-3-azatricyclo[7.3.1.0^5,^1^3]trideca-1(12),9(13),10-trien-2-one hydrochloride
• IUPAC传统名: (5S)-3-[(3S)-(3-^2H)-1-azabicyclo[2.2.2]octan-3-yl](4,4-^2H₂)-3-azatricyclo[7.3.1.0^5,^1^3]trideca-1(12),9(13),10-trien-2-one hydrochloride
• 别名: Aloxi-d3; (3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one-d3 Hydrochloride; Onicit-d3; RS-25259-197-d3

产品性质

• 外观: White Solid
• 熔点: >297-299°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

参考文献

• Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993)
• Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1993)
• Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (1993)
• Eisenberg, P., et al.: Ann. Oncol., 15, 330 (1993)
• Siddiqui, M.A.A., et al