3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid

• 产品号: O847250
• CAS号: 104239-97-6
• 分子式: C19H27NO3
• 分子量: 317.42258
• 保 存: Refrigerator

产品别名

• 标题: 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid
• IUPAC标准名: (2R,7R,10S,11S,14R,15S)-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-3-ene-14-carboxylic acid
• IUPAC传统名: (2R,7R,10S,11S,14R,15S)-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-3-ene-14-carboxylic acid
• 别名: (5α,17β)-3-oxo-4-Azaandrost-1-ene-17-carboxylic Acid Methyl Ester; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester

产品登记号

• CAS号: 104239-97-6

产品性质

• 外观: Off-White Solid
• 熔点: >260°C (dec.)
• 溶解度: Chloroform
• 溶解度: DMSO
• 溶解度: Methanol
• 溶解度: n-Propanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A novel intermediate in the synthesis of Finasteride, a 5α-reductase inhibitor used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders.

参考文献

• Bakshi., et al.: J. Med. Chem., 38, 3189 (1995)