Ouabain-d3 (Major)

• 产品号: O714502
• 分子式: C29H44O12
• 分子量: 584.65246
• 保 存: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品别名

• 标题: Ouabain-d3 (Major)
• IUPAC标准名: 4-[(1S,2R,3R,5S,7S,10R,11S,14R,15R,17R)-3,7,11,17-tetrahydroxy-2-(hydroxymethyl)-15-methyl-5-{[(2R,3S,5R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]-2,5-dihydro(^2H₃)furan-2-one
• IUPAC传统名: 4-[(1S,2R,3R,5S,7S,10R,11S,14R,15R,17R)-3,7,11,17-tetrahydroxy-2-(hydroxymethyl)-15-methyl-5-{[(2R,3S,5R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl](^2H₃)furan-2-one
• 别名: g-Strophanthin-d3; (1β,3β,5β,11α)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide-d3

产品性质

• 外观: White Solid
• 熔点: 187-190°C
• 溶解度: Methanol
• 保存条件: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alte

参考文献

• Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008)
• Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (2008)
• van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (2008)