Olopatadine N-Oxide

• 产品号: O575010
• CAS号: 203188-31-2
• 分子式: C21H23NO4
• 分子量: 353.41162
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Olopatadine N-Oxide
• IUPAC标准名: 3-[(2Z)-5-(carboxymethyl)-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]-N,N-dimethylpropanamine oxide
• IUPAC传统名: 3-[(2Z)-5-(carboxymethyl)-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]-N,N-dimethylpropanamine oxide
• 别名: 11-[3-(Dimethyloxidoamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid

产品登记号

• CAS号: 203188-31-2

产品性质

• 外观: White Solid
• 熔点: 155-157°C
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A metabolite of Olopatadine (M3). A dibenz[b,e]oxepin derivative as antiallergic agents, useful for treatment of asthma, allergic rhinitis, atopic dermatitis.

参考文献

• Mizuno, N., et al.: Drug Metabol. Pharmacokin., 17, 93 (2002)
• Polli, J., et al.: J. Pharm. Sci., 92, 2082 (2002)
• Tashiro, M., et al.: J. Clin. Pharmacol., 44, 890 (2002)
• Ohashi, R., et al.: Drug Metab. Disos., 34, 793 (2002)