NVP-BEZ 235

• 产品号: N925750
• CAS号: 915019-65-7
• 分子式: C30H23N5O
• 分子量: 469.53652
• 保 存: Refrigerator

产品别名

• 标题: NVP-BEZ 235
• IUPAC标准名: 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-1H,2H,3H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
• IUPAC传统名: 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
• 别名: BEZ 235; 4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-α,α-dimethyl-benzeneacetonitrile; 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile

产品登记号

• CAS号: 915019-65-7

产品性质

• 外观: Light Beige Solid
• 熔点: 288-289°C
• 溶解度: DMSO
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Inhibitor of phosphatidylinositol 3-kinases, P13K and mTOR.

参考文献

• Konstantinidou, G., et al.: Cancer Res., 69, 7644 (2009)
• Frederick, R., et al.: Bioorg. Med. Chem. Lett., 19, 5842 (2009)
• Pollizzi, K., et al.: Mol. Cancer, 8 (2009)