24-Nor Ursodeoxycholic Acid-d5 Methyl Ester

• 产品号: N865307
• 分子式: C24H40O4
• 分子量: 392.572
• 保 存: Refrigerator, under inert atmosphere

产品别名

• 标题: 24-Nor Ursodeoxycholic Acid-d5 Methyl Ester
• IUPAC标准名: methyl (3R)-3-[(1S,2S,5R,7R,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoate
• IUPAC传统名: methyl (3R)-3-[(1S,2S,5R,7R,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoate
• 别名: (3α,5β,7β)-3,7-Dihydroxy-24-norcholan-23-oic-d5 Acid Methyl Ester

产品性质

• 外观: Off-whtie Solid
• 溶解度: Chloroform
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: Refrigerator, under inert atmosphere

产品详细信息

详细说明 (English)

Labelled Ursodeoxycholic Acid (U850000) derivative. 24-norUrsodeoxycholic acid is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

参考文献

• Seedorf, U., et al.: J. Biol. Chem., 269, 21277 (1994)
• Stolowich, N., et al.: Biochemistry, 36, 1719 (1994)